Some doctors who treat patients with fat disorders may consider running the following tests to help identify issues that could be aggravating fat disorder symptoms and co-morbidities. Please note the scroll bars; this is a large table.

 

Lab Test NameAbbr

CPT

code

Lab Source codes for

provider to order

What a result out of the range may meanHow often to re-checkNotes
Lipid Panel - 80061 Labcorp: 303756
Quest Diagnostics: 901260
Increased risk for cardiovascular disease According to provider  
Homocysteine - 83090 Labcorp: 706994
Quest Diagnostics: 901029
Increased risk for cardiovascular disease According to provider  
Lipoprotein (a) Lp(a) 83695 Labcorp: 120188
Quest Diagnostics: 7382
Independent risk factor for cardiovascular disease According to provider  
Erythrocyte sedimentation rate (ESR) ESR 85652 Labcorp: 005215
Quest Diagnostics: 3105
Evaluate the nonspecific activity of infections, inflammatory states, autoimmune disorders To find a marker of disease or to assess treatment Marker of inflammatory mediators in the blood causing blood cells to precipitate quicker
C-reactive protein CRP 86141/0 Labcorp: 006627
Quest Diagnostics: 2320
Progressive increases correlate with increases of inflammation/injury. CRP is a more sensitive, rapidly responding indicator than ESR. To find a marker of disease or to assess treatment  
Total Hemolytic Complement CH50 86162 Labcorp: 001941
Quest Diagnostics: 9185
Complement is a system of 25 cell membrane associated and plasma proteins, which when activated produce multiple inflammatory mediators. A high level can indicate increased inflammaton. To find a marker of disease or to assess treatment.  
Chromogranin A CGA 86316 Labcorp: 140848
Quest Diagnostics: 904602
May indicate mast cell activtion disorder To find a marker of disease or to assess treatment. Do not get this lab if you are on a proton pump inhibitor (omeprazole, Nexium, etc.) which can raise chromogranin A levels. Fairly specific to mast cells.
Angiotensin converting enzyme level ACE 82164 Labcorp: 010116
Quest Diagnostics: 9136
Increase in granulomatous inflamamtion (inflammation involving groups of macrophages) To find a marker of disease or to assess treatment. Macrophages are immune cells involved in inflammation
Immunoglobulin E, Quantitative, Serum IgE 82785 Labcorp: 002170
Quest Diagnostics: ?
Total IgE levels are often elevated in patients with atopic dermatitis and the concentration of IgE tends to correlate with severity of eczema.Total IgE levels can also be elevated in patients with parasitic infections, allergic bronchopulmonary aspergillosis, or immunodeficiency. High IgE levels may correlate with exacerbation of fat disorders. To find a marker of disease or to assess treatment.  
Immunoglobulin A, Quantitative, Serum IgA 82784 Labcorp: 001784
Quest Diagnostics: 2326
IgA may be decreased in patients with chronic sinus and pulmonary lung infections or from birth, increasing a risk for infections. In people with chronic sinus or lung infections or initially.  
Immunoglobulin G, Quantitative, Serum IgG 82784 Labcorp: 001776
Quest Diagnostics: ?
May increase risk for infection. According to provider  
IgG SUBCLASSES and TOTAL IGG - 82784; 82787(x4) Labcorp: 209601
Quest Diagnostics: 9059
Some clinically significant IgG subclass deficiencies occur in patients with infections. According to provider  
Vitamin D, 25-Hydroxy 25-OH-D 82306 Labcorp: 081950
Quest Diagnostics:
At risk for bone disease; may also increase risk for infection. Every 12 weeks until normal.  
Nagalase level Nagalase None Health Diagnostics and Research
Institute (HDRI).
Link in Notes column.
There are no biomarkers for fat disorders. Many times inflammatory markers are negative. If you think you have a lot of inflammation that is hidden (not found on usual labs) please get a To find a marker of disease or to assess treatment. http://www.hdri-usa.com/tests/nagalase/
Mast Cell Tryptase Tryptase
83520
Labcorp: 004280
Quest Diagnostics 34484
Suggests mast cell activation disorder which can be treated. For a diagnosis, to monitor treatment and per provider. Must be off all H2 antagonist (ranitidine, cimetidine), all antihistamines (benadryl, zyrtec, allegra, claritin, quercetin and others) , off all NSAIDs, corticosteroids and aspirin
Plasma histamine level Histamine
83088
Labcorp: 144600
Quest Diagnostics 6586X
Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure. On initial suspicion of mast cell activation disorder and oer your provider. Must be off all H2 antagonist (ranitidine, cimetidine), all antihistamines (benadryl, zyrtec, allegra, claritin, quercetin and others) , off all NSAIDs, corticosteroids and aspirin; Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
Prostaglandin D2 FPGD2 84150 *see below Higher levels can be consistent with mast cell activation disorder. Per the provider. Must be off all H2 antagonist (ranitidine, cimetidine), all antihistamines (Benadryl, Zyrtec, Allegra, Claritin, quercetin and others) , off all NSAIDs, corticosteroids and aspirin
Factor VIII activity; also known as von Willebrand Factor Antigen Factor VIII 85240 Labcorp: 086280
Quest Diagnostics: 8353
Consistent with mast cell activation disorder when combined with other labs. Per the provider. Must be off all H2 antagonist (ranitidine, cimetidine), all antihistamines (Benadryl, Zyrtec, Allegra, Claritin, quercetin and others) , off all NSAIDs, corticosteroids and aspirin. Positive staining is seen in endothelial cells, megakaryocytes, platelets and mast cells.
24 hour urine for the histamine metabolite N-methylhistamine. Includes creatinine. - 82570, 83789 Mayo Clinic: NMH
Quest Diagnostics: 10243X
Suggests mast cell activation disorder which can be treated. Per the provider. Must be off all H2 antagonist (ranitidine, cimetidine), all antihistamines (Benadryl, Zyrtec, Allegra, Claritin, quercetin and others) , off all NSAIDs, corticosteroids and aspirin
Estrogens, Fractionated, LC/MS/MS Estrogen panel 82671 Labcorp: ?
Quest Diagnostics: 7182
High estrogens may affect fat and blood vessels. Per the provider. If menopausal and not on hormone replacement therapy. This test allows evaluation of estrogen levels that may be high because of enzymes in fat.
Heavy Metals Panel, 24-Hour Urine Heavy metal screen 82175, 83655, 83825 Labcorp: 007492
Quest Diagnostics: 107560
High heavy metals may increase inflammationand worsen a fat disorder. Per the provider.  
Thyroid Stimulating Hormone TSH 84443 Labcorp: 004259
Quest Diagnostics:
Higher TSH levels may reduce the ability to lose fat and can be consistent with fatigue. Per the provider.  
Cortisol 24-hour Cortisol 24-hour 82533 Labcorp test number 502124
(four serial samples);
Altered adrenal function; can result in fatigue, altered immune function. Per the provider. Four salivary cortisol levels: 8AM, noon, 4PM and before bed.
Helicobacter pylori Antibodies, IgG Anti-H pylori, IgG 86677 Labcorp: 162289
Quest Diagnostics: 5562
Infections generate inflammation which can exacerbate a fat disorder; an infection in the stomach may also cause pain.   Helicobacter pylori is a bacteria that can cause an infection in the stomach and cause gastritis and ulcers.
Tissue Transglutaminase, IgG tTG 83516 Labcorp: 164988
Quest Diagnostics: 901776
Detection of antibodies to aid in the diagnosis of gluten-sensitive enteropathy (GSE), such as celiac disease and dermatitis herpetiformis. If this test is positive, a gluten free diet may help with symptoms. No need for a recheck unless there is a question of diagnosis. Levels of antibodies can decrease on a gluten free diet. If you have celiac, ask your physician whether you should be tested with an IgG rather than an IgA.

 

Mayo clinic laboratories http://www.mayomedicallaboratories.com/test-catalog/print/90154)